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-The Project Gutenberg eBook of Observations on the Oleum Jecoris
-Aselli or Cod-liver Oil, by John Savory
-
-This eBook is for the use of anyone anywhere in the United States and
-most other parts of the world at no cost and with almost no restrictions
-whatsoever. You may copy it, give it away or re-use it under the terms
-of the Project Gutenberg License included with this eBook or online at
-www.gutenberg.org. If you are not located in the United States, you
-will have to check the laws of the country where you are located before
-using this eBook.
-
-Title: Observations on the Oleum Jecoris Aselli or Cod-liver Oil
- Its nature, properties, mode of preparation, &c.
-
-Author: John Savory
-
-Release Date: August 30, 2021 [eBook #66185]
-
-Language: English
-
-Produced by: Donald Cummings and the Online Distributed Proofreading
- Team at https://www.pgdp.net (This file was produced from
- images generously made available by The Internet Archive)
-
-*** START OF THE PROJECT GUTENBERG EBOOK OBSERVATIONS ON THE OLEUM
-JECORIS ASELLI OR COD-LIVER OIL ***
-
-
-
-
-
- OBSERVATIONS
- ON
- THE COD-LIVER OIL.
-
-
-
-
- OBSERVATIONS
- ON THE
- OLEUM JECORIS ASELLI,
- OR
- COD-LIVER OIL;
-
- ITS NATURE, PROPERTIES, MODE OF PREPARATION, &c.
-
-
- BY
- JOHN SAVORY,
-
- MEMBER OF THE SOCIETY OF APOTHECARIES, LATE PRESIDENT OF THE
- ROYAL PHARMACEUTICAL SOCIETY OF GREAT BRITAIN, &c. &c.
-
-
- LONDON:
- JOHN CHURCHILL, PRINCES STREET, SOHO.
- 1849.
-
-
-
-
- LONDON:
- G. J. PALMER, PRINTER, SAVOY-STREET, STRAND.
-
-
-
-
- ON
- COD-LIVER OIL.
-
-
-The introduction of a new therapeutical agent into general practice
-cannot fail to interest the medical profession and the public, and,
-profiting by the experience attained in a consideration of the manner
-in which former remedies have been brought into notice, extolled for
-their efficacy, persevered in for a time, and then gradually permitted
-to fall into disuse, and finally sink into oblivion, it will doubtless
-be useful to review the circumstances attendant upon the proposal now
-so generally entertained of the administration of the cod-liver oil for
-a variety of diseases and disorders.
-
-Although it is only of late that the attention of the public has
-been particularly drawn to this subject, principally by the zealous
-endeavours of the Medical Practitioners of Germany, it will be found
-upon inquiry that the remedy is by no means a novel proposal; nor are
-we even indebted to our foreign _savans_ for its introduction. It is to
-be traced back to the latter part of the 18th century, at which time
-it was extensively used in the Manchester infirmary, and its effects,
-as there exhibited, have been reported by the late Dr. Samuel Argent
-Bardsley, in his “Medical Reports,” 1807, 8vo. This able physician,
-who was for many years attached to the Manchester infirmary, in which
-institution chronic rheumatism formed a very large proportion of the
-medical cases under treatment, states, that for this afflicting malady,
-the Oleum Jecoris Aselli, or cod-liver oil, enjoyed a high reputation
-in Lancashire, and that thirty years previously to the time at which he
-published his useful and truly practical work, it was introduced by one
-of the physicians to the infirmary, and that its success was such as to
-induce the celebrated Dr. Percival to recommend it to his notice and
-attention as deserving of a fair and extensive trial.
-
-Dr. Percival remarks, (Works, vol. iv. p. 355,) that it was so largely
-dispensed at the Manchester infirmary, that “near a hogshead of it was
-disposed of annually;” yet its employment was almost solely confined
-to the relief of cases of chronic rheumatism, sciatica, and those
-contractions and rigidities so frequently the consequences of exposure
-to damp and cold. In these cases it was considered as superior to all
-other remedial means that had been used, and its beneficial effects
-were strikingly apparent. The operation of the oil in the first
-instance was mostly to increase the pain sustained by the afflicted,
-but this was soon succeeded by a gradual subsidence of the severity
-of the symptoms. It occasioned, particularly in irritable habits, an
-acceleration of the pulse, and diffused a glow of warmth over the whole
-frame of a very agreeable description. It promoted the secretions
-of the skin, and occasionally acted on the bowels. It was observed,
-that when its use had been persisted in for a few weeks the tongue
-became foul and the appetite impaired, so that an emetic was found to
-be necessary. It was, however, given in large doses, varying from one
-to three table-spoonfuls twice, thrice, or four times daily. It was
-also employed extensively as a liniment to the stiffened joints or
-limbs; but if soreness existed its use was forbidden; it was also never
-exhibited internally when fever was present.
-
-The oil employed at the Manchester Infirmary was obtained from
-Newfoundland, and brought thence in barrels containing from 400 to 520
-pounds in weight; it was obtained by the putrefaction of the livers
-of the fish, which were heaped together for the purpose. The oil so
-procured was, however, found to be exceedingly nauseous and offensive,
-both as regards smell and taste, so that but few stomachs could bear
-it, although a variety of means were resorted to to disguise its
-unpleasant character.
-
-Notwithstanding this, Dr. Bardsley remarks, that where it could be
-persisted in, such was the power of habit, that a relish for its
-flavour succeeded to its use, and what before was taken with such
-extreme disgust became pleasurably received. Dr. Percival says, the
-oil left upon the palate a savour like that of putrid fish, and that
-the perspiration of those taking it was strongly tainted with it. The
-oil, however, was not solely obtained from the livers of the cod-fish,
-but also from the ling (the Gadus Molva). So offensive was it found to
-be, that it was, in many instances, rendered necessary to combine it
-into the form of a liquid soap, and it is not too much to assert, that
-the efficiency of it as a remedy must have been, in no inconsiderable
-degree, impaired by the formulæ to which it was reduced.
-
-Mr. Darbey, the house surgeon of the infirmary, in a letter to Dr.
-Percival, states the discovery of the effects of cod-liver oil to
-have been accidental, and to have occurred in a patient who, using
-it externally, was induced also to take some of it internally. She
-recovered the use of her limbs, and in a few weeks was dismissed.
-No particular attention was directed to the circumstance until her
-return to the infirmary, in the course of 12 months, on account of a
-renewal of her complaint with considerable violence, which, however,
-soon subsided by the employment of the same means of relief. Dr. Kay,
-one of the physicians of the infirmary, remarked upon the case, and
-wished to test the character of the remedies in similar cases, and
-found the practice to succeed beyond his most sanguine expectations.
-It is worthy of remark, that the instances in which it was found to be
-most serviceable were those in which the perspiration was gradually
-promoted. Those who had been cripples for many years were found, after
-persisting in its use for a few weeks, not only to be able to quit
-their seats, to which they had been confined, but also to walk even
-without the aid of crutches or a stick. The effects were so remarkable,
-that application was made to the infirmary for the oil in all kinds of
-lameness, and an expenditure of not less than 50 or 60 gallons annually
-was the result. This practice was commenced about the year 1772, and
-continued for many years afterwards.
-
-One of the great evils attendant upon the introduction of a new
-remedy is the universality of its application to cases, often of very
-dissimilar nature. Its inefficiency to such a variety of purposes
-thereby speedily becomes apparent, and those disorders to which it may
-be beneficially applicable cease to be subjected to its operation:
-the novelty is gone; a prejudice against its use is created, and some
-new proposition speedily serves to banish it from a position it might
-probably, with advantage, have held in the Materia Medica.
-
-Dr. Bardsley, writing in 1807, however, gives his testimony to the
-efficiency of cod-liver oil in cases of chronic rheumatism, and says,
-“In some instances, where every other means have proved unsuccessful,
-it has operated in a manner so decidedly beneficial as to excite
-astonishment.” In many cases, however, of a mild description, it has
-not been of any advantage. In the chronic rheumatism of aged persons,
-in whom the muscles and their tendons have acquired great rigidity, so
-that the joints have become almost inflexible, it was found to be most
-serviceable. In females, also, whose powers had been much depressed
-by frequent parturition, and in whom debility towards the decline of
-life prevailed to a great degree, it has served to produce the happiest
-effects. And, in all the cases, in which it has been attended with
-benefit, it has uniformly been remarked that the consequences produced
-by the exhibition of the oil have been to occasion an increase of
-power, size, and general fatness. Its operation was far from being
-uniform, for whilst in some instances it produced increased action
-of the bowels and promoted the alvine discharges, in others it had
-a tendency to induce constipation. In some it occasioned increased
-perspiration, and in others an addition to the secretion of the urine.
-In some it produced an eruption of the skin, attended with a sense of
-prickling heat. In some few cases, none of these sensible effects were
-to be observed. When it proved serviceable, its beneficial effects
-were found to be apparent in the course of a fortnight, and if at the
-expiration of that time no good resulted, little was to be expected
-from a continuance of its use; it was, however, remarked, that when
-it began to be useful its progress was observed to be gradual, and it
-became necessary, in order to insure a cure of the patient and to guard
-against a renewal of the attack, to continue its daily exhibition for a
-period extending to not less than six or eight months.
-
-The observations of these enlightened physicians have been confirmed
-by more modern practitioners. Corroborative evidence has been adduced
-against its employment in acute cases, or those attended by active
-inflammatory action, and for its employment in chronic cases attended
-by a low inflammatory condition, or in those cases where want of power
-and diminished strength are most apparent.
-
-It is not a little remarkable, that after the able and valued testimony
-just alluded to, an agent of such therapeutical properties should have
-been allowed to fall into utter neglect in this country. Much praise
-is due to the physicians of Germany for investigating the subject, and
-practically testing its efficiency. It would be out of place here,
-and foreign to my purpose, to call attention to the various trials to
-which the remedy has been submitted and its efficient powers confirmed;
-these are to be found in the medical periodical literature of Germany
-and France, and have been translated and transferred to the pages of
-our own journals. (See “Medical Gazette,” “Lancet,” “Pharmaceutical
-Journal,” “Medico-Chirurgical Review,” “British and Foreign Medical
-Review,” “Continental and British Medical Review,” “London Journal of
-Medicine,” &c.)
-
-The cod-liver oil has been found principally efficacious in rheumatic,
-gouty, and scrophulous cases, with their accompanying manifestations of
-cutaneous eruptions and neuralgic pains. Whenever a deficiency of tone
-is apparent in the system, its employment has been found of benefit.
-Where, as in pulmonary cases, it cannot be looked upon as curative,
-it nevertheless tends to the general support of the frame, and may
-probably serve to give time for the employment of other remedies more
-especially directed to the existing disease.
-
-That cod-liver oil should produce fatness, will not occur as
-remarkable to any one who looks at its composition, the principal
-ingredient of which consists of carbon; this is present in all oils
-to a great degree, and it therefore offers a very valuable aid in
-cachectic cases, and others of diminished power and general weakness;
-hence it has been remarkably efficacious in cases of mesenteric
-disease: its powers also in exciting the lymphatic system to activity,
-in promoting also the capillary circulation, and in effecting
-absorption of scrophulous deposits, have been very striking, and
-demand the attention of every practitioner. Its effect is not merely
-increasing the deposition of fatty matter in the system, but, as Dr.
-J. C. B. Williams has asserted, increasing the muscular strength and
-action, and improving the colour of the cheeks and lips, and thereby
-affording evidence of improving the nature and condition of the blood.
-Dr. Copland, in his valuable Dictionary of Medicine, has given his
-approbation to its employment in cases of rheumatism and sciatica,
-and also in several cases of neuralgia. It would form a volume to
-give, even in abstract, the cases which, within the last three years,
-have been recorded of the efficacy of the cod-liver oil in a variety
-of affections; and my object in at all addressing the public on this
-occasion, is to point out the necessity of obtaining this remedy in its
-purest and most effective form, in order to insure its operation, and
-prevent it from falling into that desuetude which has characterized so
-many preceding remedies proposed by the profession.
-
-One of the greatest objections to its use was, as already stated, the
-exceedingly unpleasant savour it possessed, and the consequent disgust
-to its exhibition produced in persons of delicate stomach. This has in
-some measure originated from the introduction of a spurious article,
-or from the manner in which the original has been introduced. What
-could be expected otherwise than a most loathsome material, from
-livers heaped together by thousands sent over from Newfoundland, to
-deposit their oil by a course of putrefaction? The livers of other
-fish have also been found to have accompanied those of the cod, hence,
-probably, deteriorating the effect of that of the cod, or introducing
-an article calculated to produce no good result. At Berlin it is
-known that a spurious oil was introduced into the hospital, and the
-failure in its operation had well nigh superseded its use altogether. A
-genuine oil was however happily obtained, and the value of the remedy
-established. Various modes of adulteration have been detected. It has
-been found to be mixed with whale oil, the oil of the seal, &c.; and
-its offensive character may easily be estimated. The price at which
-the oil is to be obtained may probably, in some measure, serve as a
-clue to the discovery of these attempts, than which nothing can be
-more reprehensible. It is melancholy to reflect that in nothing more,
-or perhaps equally so, is adulteration practised than in medicinal
-articles. The public have little means of detecting these fraudulent
-proceedings, which ought, however, when brought to light, to be
-subjected to the severest censure and punishment.
-
-It is questionable how far these adulterations may be detected by the
-operation of the oil, since the principles of its immediate action in
-various diseases is far from having been satisfactorily ascertained.
-Its nutrient properties are known, and must be admitted in common with
-all adipose substances, and a knowledge of their constituents and
-action upon the human frame; but beyond this, namely, the specific
-qualities as adapted to counteract scrophula, rickets, rheumatic or
-gouty inflammation, neuralgia, pulmonary disorders, &c. is unknown.
-The well-ascertained effects of iodine in the relief of scrophulous
-diseases point out that substance as the immediate agent affording
-relief in those cases, but it has been ascertained that the quantity
-of iodine in the cod-liver oil is exceedingly small, being much
-beneath that which is ordinarily given in the treatment of scrophulous
-disorders, and without effect in those cases; still this small quantity
-may perhaps by nature be so incorporated in the composition of the
-oil, that although of diminished proportions, it may yet possess an
-increased power of action, as in the case of natural mineral waters.
-It may probably be truly averred, that no fictitious mineral waters,
-however admirably prepared, and however accurately constituted,
-according to the proportions of the several ingredients as ascertained
-by chemical analysis, are capable of producing the same effects as
-those by the water derived from the original spring. This may perhaps
-be the result of some electric or galvanic agency operating in its
-constitution, the place of which cannot be supplied by any substitute
-to be found in the laboratory of the chemist. Nature here manifests
-her decided superiority to the efforts of art, though ably directed
-by the hand of science. Dr. Pereira has suggested bromine to be the
-active principle in the oil, and others have attributed its efficiency
-to various phosphoric compounds. Dr. Williams refers its agency to some
-biliary principle; in short, nothing certain is known upon the subject:
-the cause may here be said to be occult, but the effect is apparent.
-Mons. Bretonneau asserts that he has obtained effects just as markedly
-beneficial to result from the use of the common whale oil, as from the
-cod-liver oil, although we know the power to be but very partially
-obtained from the liver of the cetaceous tribe.
-
-As, however, cod-liver oil is admitted to be an important medical
-agent, and as so many eminent medical practitioners have given
-their decided approbation to its employment, it is of the greatest
-consequence to have the article in the most perfect state of purity.
-Under this impression I have for a considerable time been engaged
-in various methods to accomplish this end, and without occasioning
-any change in its constituent properties, or altering the relative
-proportion of the several substances which enter into its formation,
-I have at length been enabled to obtain the oil from the fresh livers
-in a state of purity and comparative sapidity which I flatter myself
-will be universally approved. Its clearness and transparency is equal
-to that of any other oil even of a vegetable nature; its taste is
-such that it needs no admixture to disguise it, and it is therefore
-freed from the suspicion of being, by any combination, deprived of its
-essential and curative properties. It may be taken, not in the large
-doses previously administered in the Manchester Infirmary, of one, two,
-or three table-spoonfuls, two, three, or four times daily, but in that
-of one, two, or three tea-spoonfuls twice a day, and may, without
-fear of counteracting its medicinal quality, be agreeably taken in a
-small quantity of milk, or coffee, or beer. Infusion of orange-peel
-is a convenient and agreeable vehicle for its administration.
-Peppermint-water is also a convenient and proper means. If it be
-employed in the form of an emulsion, care must be taken that no syrup
-be employed into the constitution of which acid enters, as it would be
-incompatible with the alkali necessarily used to form the mixture.
-
-If the oil be pure and freed from all extraneous matters, and the
-livers from which it is procured be in a recent and not in a putrid
-state, there is little apprehension as to any disagreeable effects
-following its exhibition; in some cases, however, it has been found to
-disorder the bowels in a slight degree upon commencing its use, but
-that speedily subsides, and has rarely required the aid of remedies to
-counteract such effects.
-
-Externally it may be used by itself, or in combination with ammonia, or
-camphor, spermaceti, wax, &c., according to the intention with which
-it is employed, and which it is hardly necessary to say should be under
-the direction of a professional adviser.
-
- _143, New Bond Street,
- Feb. 21, 1849._
-
-
- LONDON:
- G. J. PALMER, PRINTER, SAVOY STREET, STRAND.
-
-
-
-
- _By the same Author._
-
-
- Third Edition, 12mo., cloth, 5_s._
-
-A COMPENDIUM of DOMESTIC MEDICINE, and COMPANION to the MEDICINE CHEST.
-Comprising Plain Directions for the Employment of Medicines――their
-Properties and Doses――Brief Descriptions of the Symptoms and Treatment
-of Diseases――Disorders incidental to Infants and Children――Directions
-for restoring Suspended Animation――Counteracting the Effects of
-Poison――A Selection of the most Efficacious Prescriptions and various
-Mechanical Auxiliaries to Medicine.
-
-By JOHN SAVORY, Member of the Society of Apothecaries, and late
-President of the Royal Pharmaceutical Society of Great Britain.
-
-
-“This is decidedly the completest work of its kind that has fallen
-under our notice.”――_Mirror._
-
-“This very useful little manual is entirely divested of scientific
-phraseology, and may be safely consulted, in cases of emergency,
-by persons residing at a distance from their medical adviser, more
-particularly where delay may be productive of fatal results.”――_Analyst._
-
-“A work which merits the attention of our parochial clergy, who
-are often called upon to act the part of the good Samaritan. In
-cases of trying emergency, when medical assistance is not at hand,
-it will be found a safe guide, the symptoms of diseases being
-clearly defined, and their appropriate remedies plainly pointed
-out.”――_Essex Standard._
-
-
- * * * * *
-
-
- Transcriber’s Notes:
-
- ――Text in italics is enclosed by underscores (_italics_).
-
- ――Obvious punctuation and spelling inaccuracies were silently corrected.
-
- ――Archaic and variable spelling has been preserved.
-
-*** END OF THE PROJECT GUTENBERG EBOOK OBSERVATIONS ON THE OLEUM
-JECORIS ASELLI OR COD-LIVER OIL ***
-
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